What Causes Sarcoidosis? Sarcoidosis is currently thought to be associated with an abnormal immune response. Whether a foreign substance is the trigger; whether that trigger is a chemical, drug, virus or other substance; and how exactly the immune disturbance is caused remain unknown. Sarcoidosis may be one common end-point caused by multiple different triggers.
Researchers supported by the National Heart, Lung, and Blood Institute and other organizations are trying to solve these mysteries. Among the research questions they are trying to answer are:
• Does sarcoidosis have many causes, or does a single agent produce it?
• In which body organ does sarcoidosis start?
• How does sarcoidosis is spread form one part of the body to another?
• Do heredity and/or environment play a role in the appearance, severity, or time-course of the disease?
• How can sarcoidosis be prevented?